Pentacyclic kinase inhibitors

Details Pentacyclic kinase inhibitors Pentacyclic kinase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/4155 (2006.01) A61P 35/00 (2006.01) C07D 491/04 (2006.01)

Patent

CA 2619276

The invention provides novel kinase inhibitors that are useful as therapeutic agents for example in the treatment malignancies where the compounds have the general formula: (I) wherein A, X, Y, Z, Ra, Rb, Rc, R1 , R2, R3 and m are defined herein.

La présente invention concerne des inhibiteurs des kinases convenant comme agents thérapeutique pour le traitement notamment des malignités. Ces composés sont représentés par la formule générale (I) dans laquelle A, X, Y, Z, Ra, Rb, Rc, R1, R2, R3 et m sont tels que définis dans les spécifications.

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