Pentafluorobenzenesulfonamides and analogs

Details Pentafluorobenzenesulfonamides and analogs Pentafluorobenzenesulfonamides and analogs

C - Chemistry, Metallurgy

07

C

C07C 311/21 (2006.01) A61K 31/16 (2006.01) A61K 31/18 (2006.01) A61K 31/275 (2006.01) A61K 31/33 (2006.01) A61K 31/357 (2006.01) A61K 31/404 (2006.01) A61K 31/416 (2006.01) A61K 31/44 (2006.01) A61K 31/5375 (2006.01) C07C 311/29 (2006.01) C07C 313/06 (2006.01) C07C 323/49 (2006.01) C07D 207/34 (2006.01) C07D 209/08 (2006.01) C07D 213/76 (2006.01) C07D 215/58 (2006.01) C07D 231/56 (2006.01) C07D 239/69 (2006.01) C07D 241/22 (2006.01) C07D 277/52 (2006.01) C07D 285/135 (2006.01) C07D 295/135 (2006.01) C07D 30

Patent

CA 2244785

The invention provides methods and compositions relating to novel pentafluorobenzenesulfonamide derivatives and analogs and their use as pharmacologically active agents. The compositions find particular use as pharmacological agents in the treatment of disease states, particularly atherosclerosis and hypercholesterolemia, or as lead compounds for the development of such agents. The compositions include compounds of general formula (I).

L'invention concerne des procédés et des compositions concernant de nouveaux dérivés et analogues des pentafluorobenzènesulfonamides, et leur utilisation comme agents pharmacologiquement actifs. Ces compositions constituent des agents pharmacologiques particulièrement utiles dans le traitement de maladies, en particulier de l'athérosclérose et de l'hypercholestérolémie, ou comme principaux composés pour le développement de ces agents. Ces compositions comprennent les composés de la formule générale (I).

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