Pentafluorobenzenesulfonamides and analogs

Details Pentafluorobenzenesulfonamides and analogs Pentafluorobenzenesulfonamides and analogs

C - Chemistry, Metallurgy

07

C

C07C 311/21 (2006.01) A61K 31/18 (2006.01) A61K 31/255 (2006.01) A61K 31/33 (2006.01) A61K 31/357 (2006.01) A61K 31/36 (2006.01) A61K 31/404 (2006.01) A61K 31/416 (2006.01) A61K 31/44 (2006.01) A61K 31/47 (2006.01) A61K 31/5375 (2006.01) C07C 309/73 (2006.01) C07C 313/06 (2006.01) C07C 323/49 (2006.01) C07D 207/34 (2006.01) C07D 209/08 (2006.01) C07D 213/76 (2006.01) C07D 231/42 (2006.01) C07D 231/56 (2006.01) C07D 239/47 (2006.01) C07D 241/22 (2006.01) C07D 277/52 (2006.01) C07D 285/135 (2006.01) C07D 295/

Patent

CA 2260777

The invention provides methods and compositions relating to novel pentafluorophenylsulfonamide derivatives and analogs and their use as pharmacologically active agents. The compositions find particular use as pharmacological agents in the treatment of disease states, particularly cancer, vascular restenosis, microbial infections, and psoriasis, or as lead compounds for the development of such agents. The compositions include compounds of general formula (I).

Cette invention a trait à des techniques ainsi qu'à des compositions en rapport avec des dérivés et des analogues de sulfamide de pentafluorophényle ainsi qu'à leur utilisation comme agents actifs du point de vue pharmacologique. Ces compositions peuvent, notamment, être employées pour leur action pharmacologique dans le traitement de certains états pathologiques comme le cancer, la resténose vasculaire, des infections microbiennes et le psoriasis, ou encore comme composés déterminants dans la mise au point desdits agents. Les compositions selon l'invention comportent des composés répondant à la formule générale (I).

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