Pentapeptides with cell growth regulatory effects and a...

Details Pentapeptides with cell growth regulatory effects and a... Pentapeptides with cell growth regulatory effects and a...

C - Chemistry, Metallurgy

07

K

530/7.06

C07K 7/06 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1298435

A B S T R A C T New pentapeptide of the formula Image I in which X1 and X2 are the same or different and are OH or NH2, Y is H or OH, X3 is CO or CH2, one of the groups Z1 and Z2 is H and the other is H or CH3, all the amino acid units being in L-configuration, with the exception that the C-terminal amino acid unit is in D-configu- ration when Z2 is methyl, and the C-terminal carboxyl group may be reduced to -CH2-OH or be in amide form, and cation complexes and salts thereof. The pentapeptide may be prepared by subjecting a protected derivative thereof to deprotection. The pentapeptide has cell growth regulatory activity.

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