Peptidase inhibitors

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 207/09 (2006.01) A61K 31/4025 (2006.01) C07D 207/10 (2006.01)

Patent

CA 2574418

The present invention relates to a series of novel compounds having the formula (I) wherein: X is NR3 or O; n is 1 or 2; A is a bicyclic carbocycle and R1 and R2 are as described herein. The compounds are useful as DPP-IV inhibitors, such as for the treatment of diabetes.

La présente invention concerne une série de nouveaux composés ayant la formule (I) dans laquelle: X représente NR3 ou O; n représente 1 ou 2; A représente un carbocycle bicyclique et R1 ainsi que R2 ont la notation définie dans la description. Les composés sont utiles en tant qu'inhibiteurs de DPP-IV, par exemple dans le traitement du diabète.

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