Peptide, adsorbent, method for production thereof, and...

C - Chemistry – Metallurgy – 07 – K

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530/7.04

C07K 7/04 (2006.01) A61M 1/36 (2006.01) B01J 20/00 (2006.01) C07K 14/705 (2006.01)

Patent

CA 1320794

ABSTRACT OF THE DISCLOSURE A peptide is disclosed which possesses an ability to bind to the human antibody to the nicotinic acetylcholine receptor and is represented by the formula: H - X - A - Y - Z (I) wherein A stands for a peptide residue, one of X and Y stands for a single bond, an amino acid residue selected from the class consisting of Asp, Glu, Lys and a divalent group represented by the formula: -NH(CH2)n?- (wherein n stands for an integer in the range of 1 to 17), or a peptide residue formed by a peptide linkage of from two to ten amino acid residues of at least one species selected from the class mentioned above, and the other of X and Y stands for an amino acid residue selected from the class consisting of Asp, Glu, Lys and a divalent group represented by the formula: -NH(CH2)n?- (wherein n stands for an integer in the range of 1 to 17), or a peptide residue formed by a peptide linkage of from two to ten amino acid residues of at least one species selected from the class mentioned above, and Z stands for a hydroxyl group or an amino group. An adsorbent having the peptide (I) immobilized on a carrier is also disclosed, as well as a method for the production of the adsorbent and a method for the use of the adsorbent.

584059

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