Peptide amides and amide dimers

Details Peptide amides and amide dimers Peptide amides and amide dimers

C - Chemistry, Metallurgy

07

K

C07K 5/04 (2006.01) A61K 31/165 (2006.01) A61K 38/04 (2006.01) C07C 237/20 (2006.01) C07K 5/065 (2006.01) C07K 5/087 (2006.01)

Patent

CA 2054651

Dkt. 91H 936 0522S ABSTRACT PEPTIDE AMIDES AND AMIDE DIMERS Peptide amide and amide dimer muscle relaxants represented by the formulae: (I) and Image (II) wherein: R is lower alkyl; R1 and R2 independently selected from the group consisting of hydrogen, lower alkyl, allyl, propargyl, aryl lower alkyl and cyclo-lower alkyl lower alkyl, or R plus one or both of R1 and R2, together with the nitrogen to which they are attached, form a heterocyclic ring having 5 to 7 member atoms; AA are independently selected from certain amino acids moieties; n is 2 to 4; x is inde- pendently 0 or 1; y is independently 1 or 2; z is 2 to 12; and and An- is a pharmaceutically acceptable anion.

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