Peptide analogs of alpha-melanocyte stimulating hormone

Details Peptide analogs of alpha-melanocyte stimulating hormone Peptide analogs of alpha-melanocyte stimulating hormone

C - Chemistry, Metallurgy

07

K

C07K 5/10 (2006.01) A61K 38/34 (2006.01) A61K 47/48 (2006.01) C07K 14/68 (2006.01)

Patent

CA 2726076

Provided herein are stable peptide analogs of the native alpha-melanocyte stimulating hormone (.alpha.-MSH) having selectivity for the melanocortin 1 receptor (MClR). Also provided herein are pharmaceutical preparations of the .alpha.-MSH peptide analogs, as well as methods of using these analogs in the treatment of medical and veterinary conditions involving MClR.

L'invention concerne des analogues peptidiques stables de l'hormone stimulant les alpha-mélanocytes (a-MSH) native qui ont une sélectivité pour le récepteur de mélanocortine 1 (MClR). Elle concerne également des préparations pharmaceutiques d'analogues peptidiques de a-MSH, ainsi que, des procédés d'utilisation de ces analogues dans le traitement d'états médicaux et vétérinaires impliquant MClR.

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