Peptide antagonists of factor viia

Details Peptide antagonists of factor viia Peptide antagonists of factor viia

C - Chemistry, Metallurgy

07

K

C07K 7/08 (2006.01) A61K 38/10 (2006.01) A61P 7/02 (2006.01) C07K 14/00 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2380633

This invention provides novel compounds which prevent or block a FVIIa mediated or associated process or event such as the catalytic conversion of FX to FXa, FVII to FVIIa or FIX to FIXa. In particular aspects, the compounds of the invention bind Factor VIIa (FVIIa), its zymogen Factor VII (FVII) and/or block the association of FVII or FVIIa with a peptide compound of the present invention. The invention also provides pharmaceutical compositions comprising the novel compounds as well as their use in diagnostic, therapeutic, and prophylactic methods.

L'invention concerne des nouveaux composés empêchant ou bloquant un processus ou un événement provoqué par ou associé au FVIIa tel que la conversion catalytique du FX en FXa, du FVII en FVIIa ou du FIX en FIXa. Dans des aspects particuliers, les composés décrits dans la présente invention lient le facteur VIIa (FVIIa), son proenzyme de facteur VII (FVII) et/ou ils bloquent l'association du FVII ou du FVIIa avec un composé peptidique décrit dans la présente invention. L'invention concerne également des compositions pharmaceutiques comprenant ces nouveaux composés, ainsi que leur utilisation dans les procédés diagnostiques, thérapeutiques et prophylactiques.

Affiliated with

Also associated with

Rating

Peptide antagonists of factor viia does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Peptide antagonists of factor viia, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Peptide antagonists of factor viia will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1494534