Peptide antiangiogenic drugs

Details Peptide antiangiogenic drugs Peptide antiangiogenic drugs

C - Chemistry, Metallurgy

07

K

C07K 14/78 (2006.01) A61K 38/39 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2329250

Peptides having the formula: A0-A1-A2-A3-A4-A5-A6-A7-A8-A9-A10 wherein A0 is selected from hydrogen or an acyl group; A10 is a hydroxyl group or an amino acid amide; and A1, A2, A3, A4, A5, A6, A7, A8 and A9 are amino acyl residues as defined herein.

L'invention concerne des peptides de la formule-A¿0?-A¿1?-A¿2?-A¿3?-A¿4?-A¿5?-A¿6?-A¿7?-A¿8?: A¿9?-A¿10? dans laquelle A¿0? est sélectionné dans le groupe constitué par hydrogène ou acyle; A¿10? est un groupe hydroxyle ou un amide d'acide aminé; et A¿1?-A¿2?-A¿3?-A¿4?-A¿5?-A¿6?-A¿7?-A¿8? et A¿9? sont des résidus d'aminoacyle, tels que définis dans le mémorandum descriptif.

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