Peptide-based immunization therapy for treatment of...

A - Human Necessities – 61 – K

Patent

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Details

A61K 39/00 (2006.01) A61K 38/00 (2006.01) A61K 38/10 (2006.01) A61K 38/17 (2006.01) A61P 9/10 (2006.01) A61P 37/02 (2006.01) C07K 7/08 (2006.01) C07K 14/775 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2443223

The present invention relates to fragments of apolipoprotein B, in particular defined peptides thereof, for immunization or therapeutic treatment of mammals, including humans, against ischemic cardiovascular diseases, as well as diagnosing the presence or absence of antibodies related to increased or decreased risk of developing ischemic cardiovascular diseases, using one or more of said peptides in an ELISA (Enzyme Linked Immuno Sorbent Assay).

La présente invention concerne des fragments de l'apolipoprotéine B, notamment des peptides définis de cette dernière, permettant l'immunisation ou le traitement thérapeutique de mammifères, y compris d'êtres humains, contre les maladies cardiovasculaires ischémiques, ainsi que le diagnostic de la présence ou de l'absence d'anticorps liés au risque accru ou réduit de développer des maladies cardio-vasculaires ischémiques, à l'aide d'au moins un peptide d'un ELISA - dosage immuno-enzymatique-.

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