Peptide-based inhibitors of hiv replication

Details Peptide-based inhibitors of hiv replication Peptide-based inhibitors of hiv replication

C - Chemistry, Metallurgy

07

K

C07K 7/06 (2006.01) A61K 38/04 (2006.01) A61K 38/08 (2006.01) C07K 7/08 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2092075

2092075 9207871 PCTABS00013 Described herein are oligopeptides useful to inhibit HIV replication in virally infected individuals. In a preferred embodiment of the invention, the oligopeptide is a D-arginine nonamer having N- and C-terminal protecting groups, which, at a 5 µm concentration, exhibits greater than 95 % inhibition of HIV replication, in a standard assay.

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