C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/18 (2006.01) A61K 31/69 (2006.01) A61K 38/04 (2006.01) A61K 38/16 (2006.01) A61P 31/14 (2006.01) C07F 5/02 (2006.01) C07K 5/06 (2006.01) C07K 5/062 (2006.01) C07K 5/08 (2006.01) C07K 5/083 (2006.01) C07K 5/10 (2006.01) C07K 5/113 (2006.01) C12N 9/50 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2376965
The present invention relates generally to novel .alpha.-aminoboronic acids and corresponding peptide analogs represented by structural Formula (I) or pharmaceutically acceptable salt forms thereof, wherein R1, R2, R3, Y1, Y2, and A are described herein. The invention is also concerned with pharmaceutical formulations comprising these novel compounds as active ingredients and the use of the novel compounds and their formulations in the treatment of hepatitis C viral infections. The compounds of the invention are inhibitors of hepatitis C viral protease.
La présente invention concerne d'une façon générale de nouveaux acides .alpha.-aminoboroniques et des analogues peptides correspondants représentés par la formule de structure (I) ou l'une de ses formes salines pharmaceutiquement acceptable. Dans cette formule, R?1¿, R?2¿, R?3¿, Y?1¿, Y?2¿, et A sont tels que décrits dans les spécifications. L'invention concerne également, d'une part des formulations pharmaceutiques dont les principes actifs sont les composés de l'invention, et d'autre part l'utilisation de ces composés et de leurs formulations dans le traitement des infections virales de l'hépatite C. Les composés de l'invention sont des inhibiteurs de la protéase virale de l'hépatite C.
Forsyth Timothy Patrick
Jagannathan Sharada
Kettner Charles A.
Bristol-Myers Squibb Pharma Company
Dimock Stratton Llp
LandOfFree
Peptide boronic acid inhibitors of hepatitis c virus protease does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Peptide boronic acid inhibitors of hepatitis c virus protease, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Peptide boronic acid inhibitors of hepatitis c virus protease will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1612146