Peptide capable of inducing immune response against hiv and...

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/49 (2006.01) A61K 38/08 (2006.01) C07K 7/06 (2006.01) C07K 14/155 (2006.01) C07K 14/16 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2173138

Herein disclosed is a peptide which is a fragment of the whole protein of HIV, the fragment being a peptide having a sequence of successive 8 to 11 amino acid residues, which corresponds to an HLA- binding motif, which actually binds to HLA and which can induce killer cells capable of attacking HIV-infected cells as target cells. The peptide is effective as an anti-AIDS agent for preventing and curing AIDS.

L'invention concerne un peptide qui est un fragment de la protéine complète de VIH, ce fragment ayant une séquence de 8 à 10 restes d'acides aminés consécutifs; le peptide correspond à un motif de liaison de HLA, est en fait fixé sur HLA, et peut induire une cellule tueuse qui cible les cellules infectées VIH. Le peptide est efficace comme moyen ou agent de prévention ou de traitement du SIDA.

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