Peptide coated dendritic cells as immunogens

Details Peptide coated dendritic cells as immunogens Peptide coated dendritic cells as immunogens

A - Human Necessities

61

K

A61K 39/385 (2006.01) A61K 39/00 (2006.01) A61K 39/12 (2006.01) A61K 39/21 (2006.01) C07K 14/47 (2006.01) C07K 14/82 (2006.01)

Patent

CA 2158281

A novel method of immunization which can be used either prophylactically or therapeutically, is described. The method comprises coating of antigen presenting cells with a peptide and administering the peptide-coated cells to a mammalian subject to provoke an immune response. Useful peptides include peptides derived from viral or bacterial antigens or mutant oncogene or tumor suppressor gene products. Immunogens, constituted by the peptide coated cells, are also described.

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