Peptide composition and method for the detection of...

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167/129, 167/37

G01N 33/569 (2006.01) A61K 39/21 (2006.01) C07K 14/16 (2006.01) A61K 39/00 (2006.01)

Patent

CA 1280363

ABSTRACT The present invention relates to a method for the detection and diagnosis of AIDS (acquired immune deficiency syndrome) ARC (AIDS Related Complex) and pre-AIDS conditions in body fluids by the use of a chemically synthesized peptide composition. The detection method includes an enzyme-linked immunosorbent assay (ELISA), an immunoradiometric assay (IRMA), and other forms of immuno assay procedures such as enzyme immuno blotting assay on nitrocellulose paper and hemagglutination assay using the peptide composition as the antigen. The preferred detection method is ELISA. The present invention also relates to a vaccine and a method for generating antibodies to HTLV-III in healthy mammals, including humans by the use of the chemically synthesized peptide composition.

544765

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