C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/47 (2006.01) A61K 38/17 (2006.01) A61P 35/00 (2006.01) C07K 14/705 (2006.01)
Patent
CA 2718949
The invention includes an isolated peptide comprising all or part of the ammo acid sequences EGKLSSNDTE GGLCKEFLHP SKVDLPR (SEQ ID NO 1), wherein the peptide inhibits Transient Receptor Potential Vamlloid 6 (TRPV6) calcium channel activity The peptides of the invention are useful for preventing or treating cancers resulting from TRPV6 calcium channel over expression.
Cette invention concerne un peptide isolé comprenant tout ou partie de la séquence d'acides aminés : EGKLSSNDTE GGLCKEFLHP SKVDLPR (SEQ ID No 1), ledit peptide inhibant l'activité du canal calcique TRPV6 (Transient Receptor Potential Vanilloid 6). Les peptides selon l'invention sont utiles pour prévenir ou traiter les cancers induits par une surexpression du canal calcique TRPV6.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Soricimed Biopharma Inc.
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