Peptide derivatives

C - Chemistry – Metallurgy – 07 – K

Patent

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530/5.04

C07K 5/04 (2006.01) A61K 38/04 (2006.01) C07C 205/02 (2006.01) C07C 205/26 (2006.01) C07C 205/43 (2006.01) C07K 5/06 (2006.01) C07K 5/08 (2006.01) C07K 5/093 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1341023

The invention concerns pharmaceutically useful trifluoromethyl ketone substituted di-, tri- and tetra-peptide derivatives of the formulae Ia, Ib, Ic set out here:W after, and salts thereof, which are inhibitors of human leukocyte elastase. Also described herein are pharmaceutical compositions containing a peptide derivative and processes and intermediates for use in the manufacture of the peptide derivatives.

500144

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