Peptide derivatives

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 14/635 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2059302

- 15 - Abstract of the Disclosure: The present invention relates to the peptides consisting of 25-50 amino acid residues and comprising the following peptide sequence: Image . . . ( I ) and amides and salts thereof. The peptides have stronger inhibitory activity against hPTH when compared with conventional inhibitors, and therefore, they are expected to be useful for the treatment of various diseases associated with calcium or phosphoric acid metabolism such as hypercalcemia and osteoporosis, or diseases associated with PTH and PTHrP.

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