Peptide derivatives and antidementia agents

Details Peptide derivatives and antidementia agents Peptide derivatives and antidementia agents

C - Chemistry, Metallurgy

07

K

530/7.06, 530/5.

C07K 7/06 (2006.01) A61K 38/07 (2006.01) A61K 38/08 (2006.01) C07K 5/103 (2006.01) C07K 5/117 (2006.01) C07K 7/16 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1339756

A novel peptide derivative having the formula: Y1-Cys-Y2 Q1-(Asn)n-Cys-Pro-A-Q2 wherein A between Pro and Q2 is Arg or Lys: Q1 is pGlu or H; Q2 is -Gly-OH or OH Y1 is H or -CO-T and Y2 is OH or T; wherein T is a thiamine derivative group is disclosed. The peptide derivative shows a remarkable nootropic effect.

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