Peptide derivatives having binding activity to modified low...

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 7/02 (2006.01) C07K 1/22 (2006.01) C07K 14/705 (2006.01) C07K 17/02 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2144104

The present invention is directed to peptide derivatives represented by the formula (I): Image (I) which can specifically bind to modified LDL in competition with scavenger receptors on macrophages and are useful in diagnosing, preventing and treating circulatory diseases caused by accumulation of modified LDL in macrophages.

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