C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/47 (2006.01) C07K 16/18 (2006.01) G01N 33/564 (2006.01) G01N 33/68 (2006.01)
Patent
CA 2272573
The invention relates to a peptide derived from an antigen recognized by autoantibodies, which peptide is reactive with autoimmune antibodies from a patient suffering from rheumatoid arthritis. The peptide according to the invention possesses a modified arginine residue. The invention also relates to antibodies against the peptide and a method of detecting autoimmune antibodies.
L'invention concerne un peptide dérivé d'un antigène reconnu par des auto-anticorps, lequel peptide réagit avec des anticorps auto-immuns provenant d'un patient souffrant de polyarthrite rhumatoïde. le peptide de l'invention possède un reste arginine modifié. L'invention concerne également des anticorps dirigés contre ce peptide, ainsi qu'un procédé de détection d'anticorps auto-immuns.
Hoet Rene Michael Antonius
Raats Jozef Maria Hendrik
Schellekens Gerardus Antonius
Van Venrooij Waltherus Jacobus Wilhelmus
Smart & Biggar
Stichting Scheikundig Onderzoek Nederland
Stichting Voor de Technische Wetenschappen
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