Peptide for diagnosing and immunizing against t. cruzi...

Details Peptide for diagnosing and immunizing against t. cruzi... Peptide for diagnosing and immunizing against t. cruzi...

C - Chemistry, Metallurgy

07

K

C07K 14/44 (2006.01) A61K 39/005 (2006.01) A61K 39/39 (2006.01) C07K 7/08 (2006.01) G01N 33/543 (2006.01) G01N 33/569 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2129747

There is disclosed an antigenic peptide that comprises at least 15 amino acids having the sequence Ala Glu Pro Lys X Ala Glu Pro Lys X Ala Glu Pro Lys X, wherein X is Pro or Ser. This peptide is useful in an ELISA assay to detect antibodies specific to T. cruzi infection and Chagas disease. This peptide is further useful in a vaccine composition for immunizing an individual to preveht Chagas disease upon exposure to T. cruzi.

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