Peptide for regulation of tissue plasminogen activator

A - Human Necessities – 61 – K

Patent

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Details

A61K 38/00 (2006.01) A61K 38/08 (2006.01) A61K 38/49 (2006.01) A61K 38/57 (2006.01) C07K 7/06 (2006.01)

Patent

CA 2453309

The present invention relates to the polypeptide, the use of the polypeptide in the prevention and/or treatment of side effects induced by plasminogen activators, specifically tPA or uPA. The invention further relates to combination compositions and/or therapy regimens, comprising the polypeptide and one or more currently used plasminogen activators, and methods to achieve improved fibrinolytic efficacy as well as reducing their side effects.

La présente invention concerne un polypeptide et son utilisation dans la prévention et/ou le traitement des effets secondaires induits par les activateurs du plasminogène et plus particulièrement tPA ou uPA. L'invention concerne également des compositions combinées et/ou des régimes thérapeutiques faisant intervenir ledit polypeptide et un ou plusieurs activateurs du plasminogène utilisés, ainsi que des méthodes permettant d'obtenir un effet fibrinolytique efficace tout en réduisant les effets secondaires.

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