Peptide fragment of lyve-1 and antibody against the same

Details Peptide fragment of lyve-1 and antibody against the same Peptide fragment of lyve-1 and antibody against the same

C - Chemistry, Metallurgy

07

K

C07K 7/08 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2518548

It is intended to provide a specific peptide fragment of LYVE-1 which can serve as an epitope of a lymphatic vessel-specific antibody, and an antibody recognizing the above peptide fragment. A peptide fragment comprising an amino acid sequence: Ser Lys Lys Thr Asp Lys Asn Pro Glu Glu Ser Lys, or the peptide fragment in which an amino acid as a linker to the C-terminal or the N-terminal thereof is added.

L'invention concerne un fragment d'anticorps spécifique de LYVE-1 pouvant servir d'épitope d'anticorps spécifique au conduit lymphatique, et un anticorps reconnaissant ce fragment. On décrit également un fragment de peptide renfermant la séquence d'acides aminés Ser Lys Lys Thr Asp Asn Pro Glu Glu Ser Lys, ou un fragment de peptide dérivé auquel on a ajouté un acide aminé, relié aux terminaisons C et N de ce fragment.

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