Peptide fragment of the respiratory syncytial virus g...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/45 (2006.01) A61K 39/155 (2006.01) A61K 47/48 (2006.01) C07K 14/135 (2006.01) C07K 14/26 (2006.01) C07K 14/765 (2006.01) C07K 17/02 (2006.01) C07K 19/00 (2006.01) C12N 15/62 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2187083

A polypeptide useful as an immunogen element and characterised in that it is carried on the peptide sequence between amino acid residues 130-230 of the G protein sequence of the human respiratory syncytial virus of sub-groups A and B, or of the bovine respiratory syncytial virus, or on a sequence at least 80 % homologous thereto. An immunogenic agent or pharmaceutical composition containing said polypeptide, and a method for preparing same, are also disclosed.

La présente invention concerne un polypeptide utilisable comme élément d'immunogène, caractérisé en ce qu'il est porté par la séquence peptidique comprise entre les résidus d'acides aminés 130 et 230 de la séquence de la protéine G du virus respiratoire syncytial humain du sous-groupe A et du sous-groupe B, ou du virus respiratoire syncytial bovin, ou par une séquence présentant au moins 80 % d'homologie avec ladite séquence peptidique. L'invention concerne également un agent immunogène ou une composition pharmaceutique contenant le polypeptide et leur procédé de préparation.

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