Peptide having anti-diabetic activity and use thereof

Details Peptide having anti-diabetic activity and use thereof Peptide having anti-diabetic activity and use thereof

C - Chemistry, Metallurgy

07

K

C07K 5/103 (2006.01) A23K 1/16 (2006.01) A23L 1/305 (2006.01) A61K 38/00 (2006.01) A61P 3/10 (2006.01) A61P 5/50 (2006.01)

Patent

CA 2739712

The present invention provides a composition (a blood glucose increase inhibitor) that has an effect of lowering blood glucose level in a hyperglycemic patient and that is therefore used to reduce blood glucose level in the patient. The present invention further provides a composition that is used to prevent or treat diseases caused by hyperglycemia, in particular, diabetes and diabetic complications (a composition for preventing or treating diseases caused by hyperglycemia, an antidiabetic), based on the above-mentioned effect. A feature of the present invention is using a peptide consisting of the amino acid sequence of Leu-Ser-Glu-Leu as an active ingredient.

La présente invention concerne une composition (un agent anti-hyperglycémique) qui est active dans la diminution du taux de glucose sanguin chez une personne qui a un taux de glucose sanguin élevé et peut ainsi être utilisée pour diminuer le taux de glucose sanguin chez la personne. Linvention concerne également une composition (une composition prophylactique ou thérapeutique destinée à des maladies associées à des taux de glucose sanguin élevés, un agent anti-diabétique) qui peut être utilisée pour la prévention ou le traitement de maladies associées à des niveaux élevés du glucose sanguin, en particulier le diabète et des complications du diabète reposant sur lactivité mentionnée ci-dessus. La composition est caractérisée en ce quelle comprend un peptide ayant une séquence dacides aminés : Leu-Ser-Glu-Leu comme principe actif.

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