Peptide having preptin functionality

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) A61K 38/08 (2006.01) A61K 38/10 (2006.01) A61K 38/17 (2006.01) A61P 5/50 (2006.01) C07K 7/04 (2006.01) C07K 7/06 (2006.01) C07K 14/47 (2006.01) C07K 14/65 (2006.01) C07K 16/18 (2006.01) C12N 5/10 (2006.01) C12N 15/63 (2006.01) G01N 33/53 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2375207

The invention relates to a bioactive mammalian peptide. In particular, it relates to a peptide secreted by the pancreatic islet .beta.-cell that stimulates insulin secretion, termed preptin. Preptin analogs, pharmaceutical compositions which contain preptin or its analogs and their use as medicaments are <i>inter alia</i> also provided.

L'invention porte sur un peptide mammalien bioactif, et notamment sur un peptide sécrété par la cellule .beta. des îlots pancréatiques qui stimule la sécrétion de l'insuline, appelée preptine. L'invention porte entre autre sur des analogues de la preptine, sur des compositions pharmaceutiques contenant la preptine ou ses analogues et sur leur utilisation comme médicaments.

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