Peptide inhibitors of human papilloma virus protein binding...

Details Peptide inhibitors of human papilloma virus protein binding... Peptide inhibitors of human papilloma virus protein binding...

C - Chemistry, Metallurgy

07

K

150/9, 530/7.06,

C07K 7/08 (2006.01) A61K 38/08 (2006.01) A61K 38/10 (2006.01) C07K 7/06 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2022394

41/RJN 17995IA TITLE OF THE INVENTION PEPTIDE INHIBITORS OF HUMAN PAPILLOMA VIRUS PROTEIN BINDING TO RETINOBLASTOMA GENE PROTEINS ABSTRACT OF THE INVENTION The present invention comprises biochemically pure polypeptides, identified from the human Papilloma virus (HPV) E7 protein, which efficiently block the binding of the HPV E7 protein to the protein encoded by the retinoblastoma gene (RBG). The polypeptides are antagonists of the biochemical interaction of the HPV E7 protein and the RBG protein. The invention is useful in the treatment of genital warts and cervical cancer. One polypeptide of the present invention (Peptide A) has an amino acid sequence of: Thr-Asp-Leu-Tyr-Cys-Tyr-Glu-Gln-Leu-Asn-Asp-Ser-Ser.

Affiliated with

Also associated with

Rating

Peptide inhibitors of human papilloma virus protein binding... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Peptide inhibitors of human papilloma virus protein binding..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Peptide inhibitors of human papilloma virus protein binding... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1963002