Peptide inhibitors of protein kinase c.gamma. for pain...

Details Peptide inhibitors of protein kinase c.gamma. for pain... Peptide inhibitors of protein kinase c.gamma. for pain...

C - Chemistry, Metallurgy

12

N

C12N 9/12 (2006.01) A61K 38/08 (2006.01) A61K 38/45 (2006.01) A61K 47/48 (2006.01) C07K 7/06 (2006.01) C07K 19/00 (2006.01) C12Q 1/00 (2006.01) C12Q 1/48 (2006.01) G01N 33/573 (2006.01)

Patent

CA 2481512

Peptide sequences derived from the V5 domain of isozymes of protein kinase C for use in pain management are described. Also described are compositions comprising the peptides for treating pain and/or inducing analgesia. Methods of pain treatment and methods of identifying compounds that mimic the activity of the peptides are also described.

L'invention concerne des séquences peptidiques dérivées du domaine V5 des isozymes de la protéine kinase C à utiliser dans la gestion de la douleur. L'invention concerne également des compositions comprenant ces peptides utilisées pour traiter la douleur et/ou induire une analgésie. L'invention concerne en outre des procédés de traitement de la douleur et des procédés d'identification de composés qui imitent l'activité des peptides.

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