Peptide inhibitors of the p33cdk2 and p34cdc2 cell cycle...

Details Peptide inhibitors of the p33cdk2 and p34cdc2 cell cycle... Peptide inhibitors of the p33cdk2 and p34cdc2 cell cycle...

C - Chemistry, Metallurgy

12

N

C12N 9/12 (2006.01) A61K 38/08 (2006.01) A61K 38/16 (2006.01) A61K 38/45 (2006.01) C07K 7/06 (2006.01) C07K 14/025 (2006.01) C07K 14/435 (2006.01) C07K 14/47 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2140379

Novel peptide and peptide mimetic ligands which act as inhibitors of p34cdc2 kinase, p33cdk2 kinase and human papillomavirus transforming protein E7 (HPV E7) are disclosed. The inhibitors are derived from the binding domains of a retinoblastoma tumor suppressor protein (Rb), p107 and a cyclin.

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