C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
530/7.06, 195/12
C12N 1/20 (2006.01) A61K 38/08 (2006.01) A61K 38/15 (2006.01) C07K 7/06 (2006.01) C07K 11/02 (2006.01) C12P 21/02 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2010777
Peptide lactone and derivatives thereof, a process for the preparation thereof and means for carrying out the process Abstract The substance hormaomycin and compounds obtainable therefrom by lactonecleavage and optionally subsequent esterification with a lower alkanol are described. Hormaomycin is obtainable by fermentation with the strain Streptomyces griseoflavus DSM 5195 and exhibits with respect to the strains Arthrobacter crystallopoietes ATCC 15481 and Arthrobacter oxydans ATCC 14358 a minimum inhibiting concentration of less than 0.001 µg/ml. Hormaomycin can be used as a medicament and for stimulating aerial mycelium formation in Streptomycetes and probably has the structure shown in formula I. Image (I)
Andres Nikolaus
Fredenhagen Andreas
Konig Wilfried A.
Rossner Ellen
Sinnwell Volker
Ag Ciba-Geigy
Andres Nikolaus
Fetherstonhaugh & Co.
Fredenhagen Andreas
Konig Wilfried A.
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