C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 31/422 (2006.01) A61P 9/08 (2006.01) A61P 43/00 (2006.01) C07D 413/12 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12P 21/02 (2006.01) C12Q 1/02 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2375605
A cDNA encoding a novel LTC4 receptor has been isolated. Provision of the novel protein, an LTC4 receptor, enabled binding experiments using the LTC4. By screening for compounds that modulate LTC4 receptor activity based on these binding experiments, development of drugs targeting the LTC4 receptor becomes possible.
L'invention concerne l'isolation d'un ADNc codant un nouveau récepteur LTC¿4?. Ce récepteur LTC¿4?, qui est une nouvelle protéine, permet de réaliser des expériences de liaison utilisant LTC¿4?. Le criblage d'un composé modifiant l'activité du récepteur LTC¿4?, sur la base de ces expériences de liaison, permet de mettre au point des médicaments ayant le récepteur LTC¿4? pour cible.
Isogai Takao
Kamohara Masazumi
Kawai Yuri
Matsumoto Mitsuyuki
Nishikawa Tetsuo
Astellas Pharma Inc.
Dennison Associates
Helix Research Institute
Yamanouchi Pharmaceutical Co. Ltd.
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