Peptide library and screening systems

Details Peptide library and screening systems Peptide library and screening systems

C - Chemistry, Metallurgy

12

N

C12N 7/01 (2006.01) A61K 38/17 (2006.01) C07H 21/04 (2006.01) C07K 1/04 (2006.01) C07K 5/083 (2006.01) C07K 5/087 (2006.01) C07K 5/103 (2006.01) C07K 5/107 (2006.01) C07K 14/435 (2006.01) C07K 14/675 (2006.01) C12N 5/10 (2006.01) C12N 15/10 (2006.01) C12N 15/62 (2006.01) C12N 15/70 (2006.01) C12Q 1/70 (2006.01) G01N 33/566 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2084411

2084411 9119818 PCTABS00008 Peptide which bind to selected receptors are identified by screening libraries which encode a random or controlled collection of amino acids. Peptides encoded by the libraries are expressed as fusion proteins of bacteriophage coat proteins, and bacteriophage are then screened against the receptors of interest. Peptides having a wide variety of uses, such as therapeutic or diagnostic reagents, may thus be identified without any prior information on the structure of the expected ligand or receptor.

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