Peptide nucleic acid monomers and oligomers

A - Human Necessities – 61 – K

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Details

A61K 38/04 (2006.01) C07K 14/00 (2006.01)

Patent

CA 2290950

Novel peptide nucleic acid (PNA) oligomers and their constituent monomers are disclosed. The PNA oligomers and linked PNAs form triple stranded structures with nucleic acids that show an increased specificity for thymidine in nucleic acid targets relative to naturally occurring nucleobases.

La présente invention concerne de nouveaux oligomères d'acide nucléique peptidique (PNA) et leurs constituants monomères. Les oligomères de PNA et les PNA liés forment des structures à triple brin avec des acides nucléiques qui démontrent, par rapport aux nucléobases d'origine naturelle, une spécificité accrue pour la thymidine dans des acides nucléiques cibles.

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