Peptide nucleic acids

C - Chemistry – Metallurgy – 12 – Q

Patent

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Details

C12Q 1/68 (2006.01) A61K 38/00 (2006.01) A61K 48/00 (2006.01) C07D 239/54 (2006.01) C07D 473/00 (2006.01) C07H 21/00 (2006.01) C07K 1/00 (2006.01) C07K 2/00 (2006.01) C07K 5/06 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) C07K 14/00 (2006.01)

Patent

CA 2109320

A novel class of compounds, known as peptide nucleic acids, bind complementary ssDNA and RNA strands more strong- ly than a corresponding DNA. The peptide nucleic acids generally comprise ligands such as naturally occurring DNA bases att- ached to a peptide backbone through a suitable linker.

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