Peptide nucleic acids and their effect on genetic material

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 5/06 (2006.01) A61K 31/505 (2006.01) A61K 38/05 (2006.01) C07D 239/54 (2006.01) C07D 403/12 (2006.01) C07D 409/12 (2006.01) C07D 417/12 (2006.01) C07D 473/00 (2006.01) C07D 487/04 (2006.01) C07K 14/00 (2006.01) C08G 69/10 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2125966

2125966 9312129 PCTABS00022 Peptide nucleic acids oligomers of formula (I) wherein n is 1 or more, particularly about 5-20 and B is independently one of the 4 nucleoside bases or their equivalents, Q and J are end groups useful in anti-sense oligomers and their use in affecting genetic material, e.g. as triplex or antisense in the treatment of disease.

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