Peptide originating in epidermal growth factor receptor (egfr)

Details Peptide originating in epidermal growth factor receptor (egfr) Peptide originating in epidermal growth factor receptor (egfr)

C - Chemistry, Metallurgy

07

K

C07K 14/71 (2006.01) C12N 5/0783 (2010.01) A61K 38/17 (2006.01) A61K 38/18 (2006.01) A61K 39/00 (2006.01) A61P 35/00 (2006.01) A61P 37/04 (2006.01) C07K 16/28 (2006.01) C12N 15/12 (2006.01)

Patent

CA 2554195

The object of the invention is to provide an EGFR-derived peptide useful for EGFR-based immunotherapy. The invention provides an EGFR-derived peptide capable of inducing both cellular and humoral immune responses and a mutant peptide thereof and a polypeptide comprising said peptide, a nucleic acid molecule encoding the same, and a pharmaceutical composition comprising the same.

L'invention concerne un peptide provenant du récepteur du facteur de croissance épidermique (EGFR), pouvant être utilisé pour l'immunothérapie fondée sur l'EGFR pour le traitement du cancer. L'invention concerne en particulier un peptide provenant de l'EGFR pouvant induire des réactions immunitaires cellulaires et humorales ou un peptide mutant de celui-ci ; un polypeptide contenant ledit peptide ; une molécule d'acide nucléique codant pour celui-ci ; et une composition médicinale contenant celui-ci.

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