A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/21 (2006.01) A61K 9/00 (2006.01) A61K 9/10 (2006.01) A61K 47/10 (2006.01) A61K 47/32 (2006.01) A61K 47/38 (2006.01)
Patent
CA 2220871
The present invention provides improved compositions for improving the chemical and physical stability of peptides and proteins. The invention provides a liquid beneficial agent formulation containing a liquid suspension comprising at least 5 % by weight beneficial agent and having a viscosity and beneficial agent size which minimizes setting of the agent in suspension over the extended delivery period.
La présente invention concerne des compositions améliorées, destinées à renforcer la stabilité chimique et physique des peptides et des protéines. Elle se rapporte à une formulation d'agent liquide bénéfique qui contient une suspension liquide comportant au moins 5 % en poids d'agent bénéfique, et dont la viscosité et la taille réduisent au minimum la sédimentation de l'agent en suspension durant la période de libération prolongée.
Carr John P.
Eckenhoff James B.
Holladay Leslie A.
Leonard John Joseph Jr.
Leung Iris K. M.
Alza Corporation
Durect Corporation
Smart & Biggar
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