Peptide proteinaceous drug nasal powder composition

A - Human Necessities – 61 – K

Patent

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A61K 47/18 (2006.01) A61K 9/14 (2006.01) A61K 9/72 (2006.01) A61K 38/00 (2006.01) A61K 38/09 (2006.01) A61K 38/23 (2006.01) A61K 38/25 (2006.01) A61K 38/29 (2006.01) A61K 38/31 (2006.01) A61K 47/20 (2006.01)

Patent

CA 2145302

A peptide proteinaceous drug nasal powder composition containing (i) an absorption accelerant comprised of a compound, or its salt, having in its molecule a group expressed by the formula (I): (see formula I) wherein, (see formula II) indicates a cyclohexane ring or a benzene ring which may be substituted at least one of its 3-position, 4-position, and 5-position and n is an integer of 1 to 3 and (ii) a therapeutically effective amount of a peptide proteinaceous drug.

Poudre permettant l'administration par voie nasale d'un médicament peptidique ou protéique. Elle comporte (i) un agent absorptif comportant un composé dont la molécule possède un groupe répondant à la formule générale (I) (dans laquelle le cycle (a) représente un cycle cyclohexane ou benzénique éventuellement substitué au moins en position 3, 4 ou 5; et n est un nombre entier compris entre 1 et 3), ou son sel, et (ii) une dose thérapeutiquement efficace d'un médicament peptidique ou protéique.

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