Peptide substrates for detecting virus-specified protease...

C - Chemistry – Metallurgy – 12 – Q

Patent

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530/5.1, 150/15.

C12Q 1/37 (2006.01) C07K 5/00 (2006.01) C07K 5/10 (2006.01) C07K 5/107 (2006.01) C12Q 1/70 (2006.01)

Patent

CA 1293591

TITLE Peptide Substrates for Detecting Virus-Specified Protease Activity ABSTRACT A method for preparing selected peptide substrates for detecting the activity of virus- specified proteases is provided. Specific tetrapeptide substrates are disclosed which are conjugates of protease-cleavable indicator groups and peptide sequences resembling picornavirus protease cleavage recognition sites.

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