A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/42 (2006.01) A61K 38/00 (2006.01) A61K 38/04 (2006.01) C07K 16/00 (2006.01) G06F 15/00 (2006.01) G06F 17/00 (2006.01)
Patent
CA 2539437
The present invention relates to the structure of Fab 4E10, e.g., as a complex with herein identified peptide KGND, herein identified as a 4E10 mimetope on gp4l, as determined by crystallographic techniques, and the confirmation that peptide KGND has a functional relevant conformation, as well as the determination of key residues on 4E10, and uses thereof and compounds and compositions therefrom. Furthermore, the invention also relates to other peptides and mimetic peptides which bind to Fab 4E10.
La présente invention a trait à une structure de Fab 4E 10, par exemple un complexe identifié comme peptide KGND, identifié comme un composé mimétique de 4E10 sur la protéine gp41, tel que déterminé par des techniques cristallographiques, et la confirmation que le peptide KGND présente une conformation pertinente fonctionnelle, ainsi que la détermination de résidus clés sur 4E10, et son utilisation et des composés et compositions associés. L'invention a également trait à d'autres peptides et peptides mimétiques de liaison à Fab 4E10.
Burton Dennis
Cardoso Rosa
Dawson Philip
Wilson Ian
Gowling Lafleur Henderson Llp
The Scripps Research Institute
LandOfFree
Peptide that binds to a broadly neutralizing anti-hiv... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Peptide that binds to a broadly neutralizing anti-hiv..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Peptide that binds to a broadly neutralizing anti-hiv... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1441598