C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 7/06 (2006.01) A61K 8/64 (2006.01) A61K 38/08 (2006.01) A61Q 19/02 (2006.01) C12N 9/02 (2006.01)
Patent
CA 2728140
Disclosed are peptides, which inhibit the enzymatic activity of tyrosinase, as well as formulations and methods for their use in the reduction of skin pigmentation, and methods of administering the inhibitory peptides in a topical formulation. The peptides are characterized by sequences RADRADC and PLG-OH. Methods of skin treatment are also provided, the methods further including use of a peptide characterized by the amino acid sequence SFLLRN.
La présente invention concerne des peptides, inhibiteurs de l'activité enzymatique de la tyrosinase, ainsi que des formulations et des procédés pour leur utilisation dans la réduction de la pigmentation de la peau, et des procédés d'administration des peptides inhibiteurs dans une formulation topique. Les peptides sont caractérisés par des séquences RADRADC et PLG-OH. L'invention concerne également de procédés de traitement de la peau par la séquence SFLLRN d'acides aminés.
Gowling Lafleur Henderson Llp
The Board Of Trustees Of The Leland Stanford Junior University
LandOfFree
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