Peptide useful in the separation and purification of...

C - Chemistry – Metallurgy – 07 – K

Patent

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C07K 7/08 (2006.01) C07K 1/22 (2006.01) C07K 4/00 (2006.01) C07K 5/08 (2006.01) C07K 5/087 (2006.01) C07K 5/09 (2006.01) C07K 5/10 (2006.01) C07K 7/02 (2006.01) C07K 7/06 (2006.01) C07K 14/00 (2006.01) C07K 16/00 (2006.01) C07K 16/06 (2006.01) G01N 33/538 (2006.01) G01N 33/543 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2179562

A peptide of formula (I) (H2N-X1-Thr-X2-CO)n-R (I) where X1 and X2, different one another, are an amino acid residue of arginine or tyrosine in configuration L or D, wherein the hydroxy group of threonine and tyrosine and the guanidine moiety of arginine may be protected by a compound conventionally used in peptide chemistry for protecting the hydroxy group and the guanidine moiety, respective n is 1,2, 3 or 4, and R, when n is 2,3 or 4, is a group suitable for forming a dimer, trimer or tetramer, while, when n is 1, R is OH, a single amino acid residue, or a peptide chain comprising up to 7 amino acid residues. The peptide of formula (I) is useful in the separation and purification of immunoglobulins.

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