Peptide vaccine for influenza virus

Details Peptide vaccine for influenza virus Peptide vaccine for influenza virus

C - Chemistry, Metallurgy

07

K

C07K 7/06 (2006.01) A61K 31/7028 (2006.01) A61K 38/08 (2006.01) A61P 31/16 (2006.01) C07H 15/00 (2006.01) C07K 14/11 (2006.01)

Patent

CA 2703646

The invention relates to the method for evaluating the potential of a chemical entity, such as an antibody, to bind to a peptide epitope derived from the divalent sialoside binding site of hemagglutinin protein of influenza virus. The invention also provides peptide epitopes 5 for use in the prevention and/or treatment of influenza or for the development of such treatment or vaccine against influenza.

L'invention concerne un procédé d'évaluation du potentiel d'une entité chimique, telle qu'un anticorps, à se lier à un déterminant antigénique peptidique provenant du site de liaison des sialosides bivalents de l'hémagglutinine, protéine du virus de la grippe. L'invention propose également des déterminants antigéniques peptidiques 5 utilisables dans le cadre de la prévention et/ou du traitement de la grippe ou pour la mise au point d'un tel traitement ou vaccin contre la grippe.

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