C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/605 (2006.01) A61K 38/22 (2006.01) A61K 38/26 (2006.01) A61P 25/28 (2006.01) C07K 14/575 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2420550
The present invention involves peptides with memory enhancing activity that are homologous to glucagon, Exendin- and glucagon-like peptides; functional analogs, derivatives, fragments and mimetics of these peptides; methods of synthesizing and modifying such peptides; methods of using such peptides to treat nervous system or neurological disorders and to facilitate learning and memory in mammals; and methods of delivering such peptides to mammals for treatment of nervous system or neurological disorders and for facilitation of learning and memory.
L'invention concerne des peptides possédant une activité d'accroissement de la mémoire, et qui sont des homologues des peptides glucagon, Extendin-, ou de type glucagon; elle concerne encore des analogues, dérivés, fragments et mimétiques, fonctionnels, de ces peptides, de même que des procédés d'utilisation de tels peptides pour traiter des troubles neurologiques ou du système nerveux et pour faciliter l'apprentissage, et l'entraînement de la mémoire chez des mammifères. L'invention concerne enfin des procédés d'apport de tels peptides, à des mammifères, dans le traitement de troubles neurologiques ou du système nerveux, et dans la facilitation de l'apprentissage, et de l'entraînement de la mémoire.
During Matthew
Haile Colin N.
Riches Mckenzie & Herbert Llp
Thomas Jefferson University
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