Peptides acting as both glp-1 receptor agonists and glucagon...

Details Peptides acting as both glp-1 receptor agonists and glucagon... Peptides acting as both glp-1 receptor agonists and glucagon...

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 31/7088 (2006.01) A61K 38/17 (2006.01) A61K 48/00 (2006.01) A61P 3/10 (2006.01) C07K 14/47 (2006.01) C07K 14/605 (2006.01) C07K 16/18 (2006.01) C12P 21/02 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2462462

The invention provides polypeptides that act both as an agonist of the GLP-1 receptor and an antagonist of the glucagon receptor. Such polypeptides are useful for treating individuals with type 2 diabetes or other metabolic disorders.

L'invention concerne des polypeptides jouant à la fois le rôle d'agonistes du récepteur GLP-1 et d'antagonistes du récepteur de glucagon. Ces polypeptides sont utiles pour traiter des individus atteints de diabète de type 2 ou d'autres troubles du métabolisme.

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