Peptides aiding nerve regeneration

Details Peptides aiding nerve regeneration Peptides aiding nerve regeneration

A - Human Necessities

61

K

A61K 38/08 (2006.01) C07K 14/695 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2029268

- 22 - Abstract of the Disclosure A method of treating muscle wasting which includes the step of administering to a mammal an amount of a heptapeptide of the formula: A1-A2-A3-A4-Phe-Arg-Trp-A5 wherein A1 is H or acetyl; A2 is Ala, D-Ala, Nle, or Met; A3 is Glu or Gln; A4 is His or Tyr; and A5 is NH2, Gly-NH2, or D-Ala-NH2;, provided that when A3 is Glu and A4 is His, A2 cannot be Met or Nle, or a pharmaceutically acceptable salt thereof sufficient to prevent muscle wasting.

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