Peptides and antibodies to muc 1 proteins

Details Peptides and antibodies to muc 1 proteins Peptides and antibodies to muc 1 proteins

C - Chemistry, Metallurgy

07

K

C07K 16/30 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) A61P 35/00 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C07K 16/28 (2006.01) C12N 5/12 (2006.01) C12Q 1/02 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2442531

The invention relates to methods of inhibiting proliferation or growth of tumor cells and/or inducing cell death in cancer cells. This invention relates to the use of antibodies, hybridomas and pharmaceutical compositions containing same, for inhibiting growth or proliferation and inducing death in epithelial, colon, lung, breast and ovarian tumor cells or other cells which express MUC1 proteins.

L'invention concerne des méthodes d'inhibition de la prolifération ou de la croissance de cellules tumorales et/ou d'induction de l'apoptose dans des cellules cancéreuses, ainsi que l'utilisation d'anticorps, d'hybridomes et de compositions pharmaceutiques contenant ceux-ci, dans le cadre de l'inhibition de la croissance ou de la prolifération de cellules tumorales ci-dessous et de l'induction de l'apoptose dans des cellules tumorales épithéliales, du côlon, des poumons, du sein et des ovaires ou les autres cellules qui expriment des protéines MUC1.

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