Peptides and compositions for prevention of cell adhesion...

C - Chemistry – Metallurgy – 07 – K

Patent

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C07K 14/435 (2006.01)

Patent

CA 2748121

Compositions comprising an isolated peptide, which may for example optionally comprise a sequence selected from the group consisting of FDYDWY, SFSQNKSVHSFDYDWYNVSDQADLKN or CSFSQNKSVHSFDYDWYNVSDQADLKNC, or any cyclized version thereof, and methods of using same, including for treatment of or prevention of formation of microbial biofilms and against adhesion of a cell to a surface.

L'invention concerne des compositions comprenant un peptide isolé qui peut, par exemple comprendre éventuellement une séquence sélectionnée dans le groupe constitué par FDYDWY, SFSQNKSVHSFDYDWYNVSDQADLKN ou CSFSQNKSVHSFDYDWYNVSDQADLKNC, ou une version cyclisée quelconque de cette dernière, et des procédés d'utilisation permettant de traiter ou de prévenir la formation de biofilms microbiens, et de lutter contre l'adhésion cellulaire sur une surface.

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